Chronotype and Genetics: How Our Genes Influence Our Biological Clock

DNA kit adntro box

Discover your genetic predisposition in several areas of wellness such as sleep, ayurveda and much more with the most complete DNA kit.

Already genotyped? Upload your RAW DNA for free!

Circadian rhythms are fundamental cyclical processes that occur in most living organisms, including humans. The circadian rhythm refers to an underlying 24-hour physiological cycle that occurs in most living organisms. In humans, there are clear daily cyclical patterns in core body temperature, hormonal systems, and most other biological systems.

These cycles are important for many molecular and behavioral processes. In particular, circadian rhythms are important for regulating sleep patterns, allowing the organism to anticipate and adapt to regular environmental changes, optimizing its biological functions for different times of the day. For example, the release of melatonin, a hormone that induces sleep, increases during the night in response to darkness, helping to prepare the body for rest.

Types of chronotypes

When we talk about chronotype, despite each species having an endogenous circadian rhythm, there are significant natural variations in the population. People with later circadian rhythms tend to sleep better if they go to bed late and wake up later, so they are often called "owls" or "night people." Those with earlier rhythms tend to feel sleepy earlier at night and wake up early in the morning. The rest of the population falls between these two extremes.

Chronotype and genetics

This dimension of circadian timing, or chronotype, is a behavioral consequence of the organism's underlying cycles. For this reason, depending on your chronotype, your peak performance hours will vary:

  • If you are a morning person, sleep will overtake you between 9:00 PM and 9:30 PM, and by 4:00-5:00 AM, you will be up and moving.
  • If you are more of a morning person than an evening person, your schedule won't be as extreme as the one above. Your body will prompt you to go to bed between 9:30 PM and 10:45 PM, waking up optimally between 5:00 AM and 6:30 AM.
  • If you have an intermediate chronotype, you will tend to go to bed between 10:45 PM and 12:45 AM, waking up between 6:30 AM and 8:30 AM.
  • If you are more of an evening person than a morning person, you will tend to go to bed between 12:45 AM and 2:00 AM, and you will be up and moving between 8:30 AM and 10:00 AM.
  • If you are an evening person, you will tend to go to bed between 2:00 AM and 3:00 AM, waking up optimally between 10:00 AM and 11:30 AM.

The role of genetics in chronotype

Factors such as age and gender, as well as levels of ambient light, account for a substantial proportion of the variation in chronotype, but genetic variation is also an important contributor.

The PER2 gene (Period Circadian Regulator 2) is one of the genes involved in the regulation of the circadian rhythm as it plays a crucial role in internal synchronization.

Genetic variants located in this gene, among others, are associated with the variability of chronotypes that exist in the human species, highlighting their importance in these biological processes.

Chronotype and health

The importance of sleep is indisputable. Alterations in circadian rhythms and chronotype can have significant health implications. For example, a mismatch between a person's chronotype and their work or school schedule can lead to insufficient sleep and a higher incidence of sleep disorders. Additionally, changes in chronotype have been found to be related to the risk of developing metabolic diseases, such as diabetes, and psychiatric disorders, such as depression.

Want to know what your genetics say about your chronotype? Find out with ADNTRO's genetic tests.

Share this post

More interesting articles

saxenda
Pharmacogenetics and pharmacogenomics

Saxenda

Saxenda (liraglutide as active ingredient) is mainly used in the treatment of type 2 diabetes. But what has really caught the attention of

Read more "
DNA kit adntro box

Discover your genetic predisposition in several areas of wellness such as sleep, ayurveda and much more with the most complete DNA kit.

Already genotyped? Upload your RAW DNA for free!

Other topics

Share this post:

Facebook
Twitter
LinkedIn
WhatsApp
E-mail

Get a 10% discount!

An Investment
for all Life

DNA test with saliva sample
More complete analysis
Ancestry, Nutrigenetics, Traits and Diseases,...
Already genotyped?

If you have taken a test with 23andMe, MyHeritage, Ancestry.com and others, you can upload your DNA for free at 23andMe, MyHeritage, Ancestry.com and others.

Digestive Medicine

For digestive clinics or physicians. Provides information on the genetic predisposition to develop diseases of the digestive system- such as Chron's, Inflammatory Bowel Disease among many others - as well as intolerances. This supports a possible early diagnosis and prevention. The results of this study are very positive, allowing for more precise and personalized interventions to improve the quality of life of the patients.

nutrition

Cardio

The applicability and importance of the PRSs in cardio is endorsed by the American Heart Association (AHA). The applicability of PRS is made possible thanks to this tool that helps in the cardiovascular disease prevention: identifying patients with a higher genetic risk of developing conditions such as diabetes, thromboembolism, hypercholesterolemia, and coronary artery disease (CAD), among others, enabling early interventions and preventive measures to improve patients' cardiovascular health.

integrate genetics into your practice

Biobanks, Pharmacies and CROs

Access and consultation of genetic data relevant to health and pharmacology. Thanks to this tool, it is possible to know the predisposition of patients to suffer adverse effects and what dose adjustments are necessary for more than 150 drugs, thus improving safety, efficacy and treatment personalization. This information is backed by Stanford University and approved by the FDA and gives solutions for biobanks, and research organizations.

integrate genetics into your practice

Dermatology

Specialized for dermatological clinics, this service provides information on dermatogenomics: skin sensitivities, efficacy of various topical and oral treatments, essential vitamins and minerals for skin health, dermatological conditions, skin types and more data to help you customize your skin care recommendations.

integrate genetics into your practice

Fitness and wellness centers

Genetic analysis allows for the design of personalized training programs that, taking into account genetic characteristics focused on the world of sports, such as muscle fiber types and predisposition to injuries, maximize performance and reduce the risk of injuries. Additionally, by considering genetic factors related to sleep and longevity, recommendations can be offered for a healthy and sustainable lifestyle.

integrate genetics into your practice

Nutri & Fitness

The practical application of nutrigenomics allows you to differentiate yourself from the competition by offering your patients personalized and accurate information on genetic predispositions to food intolerances.The results of this approach allow the design of dietary plans completely adapted to the genetic profile of the patient. This approach makes it possible to design dietary plans completely adapted to the individual needs maximizing results and providing an exceptional and differentiated service in the field of nutrition.

integrate genetics into your practice

Neuro

Very useful for psychiatric clinics and psychological clinics. Provides information on the genetic predisposition to develop nervous system diseases and mental disorders, such as Alzheimer's, Parkinson's, schizophrenia, bipolar disorder and OCD, among others. This supports a possible early diagnosis and prevention of these conditions, allowing for more precise and personalized interventions for improve the quality of life of patients.

integrate genetics into your practice

Start a unique journey inside your DNA

Kind regards from ADNTRO team