Genetic curiosities

The importance of genetic diversity | DNATRO

Do you know the importance of genetic diversity? Do you know its relationship with diseases? In this post we tell you about it!

ADNTRO's science team ·April 12, 2021 ·1 min read

Updated on September 23, 2024

Formerly the upper classes, especially the kings, married each other in order to preserve their “pure” blood, strengthen the line of succession and maintain power in the family. What they did not know is that this “purity” conceived heirs with a high probability of suffering from diseases. Have you ever wondered why?

The main reason is genetic diversity. Inbreeding in real families reduced the genetic diversity of the children since, if an individual has a child with a relative, the paternal and maternal alleles will be very similar and this similarity will be strengthened generation after generation.

The importance of genetic diversity

And you may wonder, what does genetic diversity have to do with diseases? Much. There are numerous diseases that follow a recessive inheritance pattern, that is, for the disease to manifest both alleles (“letritas” inherited from the mother and part of the father) must be risk alleles, “defective alleles” ”.

For this reason, if your genetic diversity is high, the probability that you inherit two “defective” alleles decreases. And one way to quantify genetic diversity is with the heterozygosity ratio (available in the section on Ancestry).

 quantifying genetic diversity

ADNTRO results are for research and educational purposes. They do not constitute a medical diagnosis and do not replace consultation with a healthcare professional.

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