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The term sleep refers to both the act of sleeping and the activity of the mind that takes place during that period of rest. Is a biological necessity which enables restore the physical functions and psychological essential for full performance. While we sleep, a large number of activities take place such as neural reorganization, consolidation and storage of relevant memories.

In the field of sleep, there are various pathologies that can affect physical health, personal life (family, work and social life) and even mental health in the most severe cases.

The best known is the insomnia. There are two types, the transient and the chronic. The first is the most common. It is caused by stress, anxiety, jet lags, worries ... I would dare to say that we have all experienced this sleep disturbance at some point in our lives and we do not have to be alarmed for that. What should worry us is if said alteration becomes recurrent, that is, if we suffer from insomnia chronic.

The latter term includes problems in reducing the ability to sleep, either due to problems in falling asleep (chronic onset insomnia) or due to problems maintaining sleep (chronic maintenance insomnia).

Recently, due to the current situation with respect to the COVID 19a third type of insomnia has been defined, namely covid-somnio or coronasomnia. The number of people suffering from insomnia has increased in times of pandemic. Experts accuse it of changes in our lifestyle (many hours at home lying down, reduced physical activity and reduced mobility), uncertainty, worry, stress and anxiety.

sleep care

Be that as it may, insomnia reduces our hours of sleep that are necessary to restore the functions of our body (minimum 4 hours sleep). However, it is surprising how the natural sleep hours throughout the population. There are people who need between 9 and 10 hours of sleep to be energetic and others who with just 5 hours do not have even a dark circle.

There is a genetic component that affects both natural hours of sleep and insomnia, but they are not the only sleep characteristics associated with genetic variants.

Genetic associations related to snoring (snoring) and sleep-wake rhythms (chronotype or biological clock). Sleep, like other body functions, is regulated by the well-known biological clock or circadian rhythm (24-hour cycle) that adapts our physiology to different phases of the day. This "machinery" establishes what time of day our propensity to sleep increases, sending a signal to an endocrine gland located in the brain to start the production of melatonin (the hormone responsible for the day / night cycle).

melatonin production

Normally, the sleep regulatory centers receive the activation signal in the evening and are progressively deactivated in the morning. However, the biological clock can be influenced by genetic factors (among other reasons) that classify the population into two large groups: people in the morning and people at night.

At ADNTRO We are working to offer you a new section, a section of the dream. In it you will be able to know your genetic predisposition to suffer insomnia, to snore, to sleep more or less hours naturally, the chronotype where you belong and if you tend to be sleepy throughout the day according to your genetics. !Be part of ADNTRO and we will keep you informed of all updates!

Remember that if you are already genotyped with another company, you can upload your RAW DNA data for free.

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For digestive clinics or physicians. Provides information on the genetic predisposition to develop diseases of the digestive system- such as Chron's, Inflammatory Bowel Disease among many others - as well as intolerances. This supports a possible early diagnosis and prevention. The results of this study are very positive, allowing for more precise and personalized interventions to improve the quality of life of the patients.

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The applicability and importance of the PRSs in cardio is endorsed by the American Heart Association (AHA). The applicability of PRS is made possible thanks to this tool that helps in the cardiovascular disease prevention: identifying patients with a higher genetic risk of developing conditions such as diabetes, thromboembolism, hypercholesterolemia, and coronary artery disease (CAD), among others, enabling early interventions and preventive measures to improve patients' cardiovascular health.

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Access and consultation of genetic data relevant to health and pharmacology. Thanks to this tool, it is possible to know the predisposition of patients to suffer adverse effects and what dose adjustments are necessary for more than 150 drugs, thus improving safety, efficacy and treatment personalization. This information is backed by Stanford University and approved by the FDA and gives solutions for biobanks, and research organizations.

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Specialized for dermatological clinics, this service provides information on dermatogenomics: skin sensitivities, efficacy of various topical and oral treatments, essential vitamins and minerals for skin health, dermatological conditions, skin types and more data to help you customize your skin care recommendations.

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Genetic analysis allows for the design of personalized training programs that, taking into account genetic characteristics focused on the world of sports, such as muscle fiber types and predisposition to injuries, maximize performance and reduce the risk of injuries. Additionally, by considering genetic factors related to sleep and longevity, recommendations can be offered for a healthy and sustainable lifestyle.

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The practical application of nutrigenomics allows you to differentiate yourself from the competition by offering your patients personalized and accurate information on genetic predispositions to food intolerances.The results of this approach allow the design of dietary plans completely adapted to the genetic profile of the patient. This approach makes it possible to design dietary plans completely adapted to the individual needs maximizing results and providing an exceptional and differentiated service in the field of nutrition.

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Very useful for psychiatric clinics and psychological clinics. Provides information on the genetic predisposition to develop nervous system diseases and mental disorders, such as Alzheimer's, Parkinson's, schizophrenia, bipolar disorder and OCD, among others. This supports a possible early diagnosis and prevention of these conditions, allowing for more precise and personalized interventions for improve the quality of life of patients.

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