How was your trip with ADNTRO in 2023?

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In this exciting journey inside your genetic code, we want to express our sincere appreciation for allowing us to be your compass in the world of DNA. This year has been extraordinary, full of groundbreaking discoveries and breakthroughs, and we are excited to share with you the shining jewels of our progress.

Here is a summary of the most important updates we have implemented over the last year. Always remember that "Your DNA doesn't change, but the progress of science is continuous". With ADNTRO, your genetic code is still the story of your uniqueness, but with each new update, we bring you a little closer to the future of genomics.

Welcome to your recap of the year 2023 with ADNTRO. Let's explore together the wonders of your updated DNA!

JANUARY

We start the year by expanding our health section, adding the predisposition to suffer from Tourette Syndrome, a neuropsychiatric disorder characterized by repetitive, involuntary movements and vocalizations known as tics. These tics can range from mild to severe and can interfere with daily activities and social interactions.

Tourette syndrome is polygenic and highly hereditary. If one of the parents suffers from it, there is a high probability that their offspring will inherit the genetic predisposition to develop it. This neuropsychiatric disorder affects approximately 1 in 160 people.

FEBRUARY

In February, we update our report on Alzheimer's. This disease is the most common form of dementia (between 60-80% of cases) and is therefore considered a major neurocognitive disorder. It encompasses a set of concurrent symptoms whose main symptom is severe cognitive impairment that affects the functioning and activities of daily living of sufferers.

Cognitive deficits associated with Alzheimer's disease include memory problems, orientation problems, impaired reasoning and decision making.

MARCH

We add a genetic study that helps to understand the predisposition to Osteoporosis. The disease affects approximately 25.5 million women and 6.5 million men over the age of 50 in the European Union.

In addition, we include new variants in the predisposition to serotonin levels and susceptibility to COVID:. Keeping your results updated with new variants found.

APRIL

In April, we updated our addiction section by including more useful information and added two studies that help understand the genetic predisposition to gambling addiction and sugar addiction. we update our addictions section including more useful information and we add two studies that help to understand the genetic predisposition to gambling addiction and the sugar addiction.

Genetics can influence the likelihood of a person developing an addiction and its severity. Various genes play a role in regulating the release of neurotransmitters such as dopamine, which can impact reward-seeking behavior. However, environmental factors like stress and social influence also play a significant role in the development of addictions.

MAY

The skin is the protagonist in the month of May. We improved the skin section and we add a new study that helps to understand the genetic predisposition to facial blemishes.

Genetics can influence the appearance and health of our skin. A new GWAS (Genome Wide Association Study), conducted on a cohort of 2844 Dutch Europeans, identified genes that influence facial pigmented spots.

Although genetics may be an important factor, it is always necessary to protect our skin from the sun and adopt healthy habits, which translates into healthier, more radiant skin.

JUNE

We continue to enhance our skin reports, and this month we added two new studies that help understand the response to tanning and tendency to sunburn based on your genetic predisposition.

The production of melanin, the pigment responsible for the color of our skin, is key to the response to tanning as well as the tendency to experience sunburns. This process is triggered by the ultraviolet radiation from the sun, which stimulates melanin production in melanocytes.

JULY

We updated the entire section of injury and we add a new study that helps you know your genetic predisposition to suffer ankle injuries. In the exciting world of sports, ankle injuries are a common concern for many athletes, so it is crucial to take care of this part of the body and take precautions.

Although sudden movements are the main cause of injury, there are other risk factors such as uneven surfaces, improper footwear, and genetics, which can influence risk, severity and recovery time.

AUGUST

In August, we released a major update that brings our food intolerances to new levels of precision.

Genetic food intolerances are those that occur when a person inherits genetic variants that reduce his or her ability to process certain foods, which can have a significant impact on his or her life.

In the celiac disease analysisIn the celiac disease analysis, we've enhanced our precision. By examining genetic variants in the HLA-DQA1 and HLA-DQB1 genes, we can significantly improve our results. If you want to learn more about HLA-DQ haplotypes, you can do so in our article Decoding the Genetic Predisposition of Celiac Disease: HLA-DQ Haplotypes.

Decoding the Genetic Predisposition of Celiac Disease: HLA-DQ Haplotypes.

In our lactose intolerance report, we've enhanced precision and offer a deeper insight, providing a nuanced understanding of your lactose intolerance results.

About the hereditary fructose intolerance (IHF), we increase the accuracy of the results and the way to analyze it, being possible to know if you are a carrier of genetic variants associated with IHF that do not make you intolerant, but that you could transmit to your offspring.

SEPTEMBER

This month marked a milestone with the launch of the ADNTRO Community, an exclusive section for all subscribers where they can access unique reports.

Within the community, users can request their Nutrigenetic Report, an innovative report that serves as a valuable guide to interpret their genetics and implement changes in diet and lifestyle. Its purpose is to prevent and/or treat various health conditions.

Furthermore, the ADNTRO Community includes intriguing and unique reports such as the "Genetic Bonsai," DNA art customized for each user, or a playful dive into J. Conway's "Game of Life," among others.

In addition, we updated our report of Ancestral composition so that you can discover the traces that ancient migratory movements have left in your DNA. This analysis delves into many past generations to reveal the mosaic of humanity that makes up your DNA from a historical perspective, and has the potential to illustrate the movements and interactions of your ancestors from hundreds or even thousands of years ago.

And if all that wasn't enough, we've added new studies that help understand muscle damage after exercise. We provide insights into your genetic predisposition for elevated levels of creatine kinase and lactate dehydrogenase, as well as your levels of muscular inflammation.

OCTOBER

In honor of World Breast Cancer Day, we delved into a groundbreaking study on the genetic risk of developing this disease. Breast cancer afflicts 1 in 8 women during their lifetime, with only 10% of cases being hereditary, while the remaining 90% are sporadic.

Breast cancer occurs when some cells found in the mammary gland and breast tissues begin to grow abnormally. These cells divide faster than healthy cells and continue to accumulate, forming a lump or mass. The cells can spread (metastasize) through the breast to the lymph nodes or to other parts of the body.

In this month, we also celebrated that we were selected for the Google for Startups Growth Academy: AI for Health 2023! An exciting opportunity to accelerate our growth and make a significant impact on the healthcare industry.

NOVEMBER

This month, we marked a before and after with GeneAIa revolutionary experience that allows members of the ADNTRO Community to talk directly to your DNA thanks to the power of artificial intelligence.

What diet is most suitable for you? What eye color will your children have? What is the ideal workout routine to achieve your goals? With GeneAI, you can immerse yourself in a unique experience where you will directly converse with your DNA and explore the fascinating wonders it holds.

GeneAI ADNTRO talks to your DNA

DECEMBER

We are launching our last update of the year: genetic predisposition to common male pattern baldnessa common concern for many people, affecting approximately 40% of the European population over the age of 35.

And you might wonder, why only male pattern baldness? Given the limited scientific evidence of genetic variants associated with female baldness, we decided to assess only the predisposition to male pattern baldness, for which there is a well-established scientific foundation.

Additionally, the Life Sciences Review included us in its annual list recognizing the ' TOP 10 Genomic Solutions Providers in Europe,' a genuine source of pride that was the icing on the cake to a year filled with hard work, dedication, and updates.

What does the future hold for us? Well, we don't want to reveal all our secrets just yet, but we can tell you that we're working on incredible updates such as the DAO enzyme or the MTHFR gene, along with surprising innovations in other areas. There's much more on the horizon for ADNTRO, and we can't wait to share it with you.

What does the future hold? Well, we don't want to reveal all our secrets just yet, but we do want to tell you that we are working on amazing upgrades such as DAO enzyme or the gene MTHFRplus surprising developments in other areas. There's much more on the horizon for ADNTRO, and we can't wait to share it with you.

If you are not yet a part of our community, we invite you to join us by purchasing your DNA test or uploading your RAW DNA data.

Thank you for being part of this incredible journey with ADNTRO! Until the next chapter of your genetic story.

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