Genotyping analyzes those variants of our genome that are polymorphic, that is, they show great variability between people and are very common in general (> 1% in the population). Genetic association studies (GWAS) are fundamentally based on this type of analysis and help to determine our predisposition to different diseases as well as to determine phenotypic variations in individuals.

Genotyping techniques analyze approximately 700,000 positions in our DNA; compared, whole genome analysis (WGS), in which all your DNA is analyzed (the three billion base pairs) and therefore allows the detection of rare variants in the population; These rare variants tend to have a high impact on the development of diseases, susceptibilities to diseases and on the response to treatments and it is the most used technique in genetic research in the world.

Surely you have seen our Home Kit, our genetic tests with a cheaper price.

With these microarray kits we perform genotyping, with which approximately 700,000 positions of your DNA are read, which is sufficient for some common traits but cannot be used for diagnosis or detection of rare variants.

With the complete sequencing of the genome (Whole Genome Sequencing) we can analyze its complete DNA (3,200,000,000 positions).

Our own comparative studies between 4x and 30x show a quality level of 90% + with differences in those regions and variants that are more difficult to detect that can only be determined with 30x

The difference lies in the level of your DNA coverage - 4x coverage means that each position of your DNA letter sequence has been read an average of 4 times. To be able to make a clinical diagnosis, a greater coverage is necessary to determine your genetic variants, of at least 30x. That is, each DNA position is read at least 30 times on average.

Our own comparative studies between 4x and 30x show a quality level of 90% + with differences in those regions and variants that are more difficult to detect that can only be determined with 30x

From ADNTRO we send you a kit to your home to collect the DNA sample (a simple saliva sample, 2ml) - The delivery to your home, as well as the return of the sample to the laboratory, is included in the price.

From your arrival at the laboratory (approx. 5 business days in Europe), your results will be ready in 4 weeks.

You can access your results online, explore all sections of ADNTRO (including health and pharmacogenetics) and download files with your genetic information.

The possibility of a genetic consultation with a professional team certified by the European Union in molecular genetics is offered; As well as by the DNATRO bioinformatics team. The consultation will be via email where you can solve your doubts regarding your results and we will help you in everything that is necessary.

No clinical diagnosis is offered, for which you should consult with your doctor

If you decide to carry out an exome or genome, we give you the possibility of carrying out targeted analysis of genes in which we will tell you the variants detected in a specific subset of genes. You can contact us by filling out this contact form for more details.

We will give you several formats so you can explore your DNA.

For the WGS High-Pass you will receive:

• FASTQ
• BAM and BAI
• VCF SNP
• VCF CNV
• VCF INDEL
• Others: XLS, PDF of reports, ...
• Bonus: Circus Plot
• Diagnostic report (contracted separately)

For the WGS Low-pass:

• FASTQ
• BAM and BAI
• VCF