{"id":1041,"date":"2020-08-11T17:30:12","date_gmt":"2020-08-11T15:30:12","guid":{"rendered":"https:\/\/www.adntro.com\/?p=1041"},"modified":"2026-03-26T09:56:42","modified_gmt":"2026-03-26T08:56:42","slug":"farmacogenetica-conoce-como-te-afectan-los-medicamentos","status":"publish","type":"post","link":"https:\/\/adntro.com\/de\/blog\/pharmakogenetik\/pharmakogenetik-know-how-medikamente-beeinflussen-sie\/","title":{"rendered":"Pharmakogenetik: Erfahren Sie, wie Medikamente Sie beeinflussen."},"content":{"rendered":"<figure class=\"wp-block-embed is-type-video is-provider-youtube wp-block-embed-youtube wp-embed-aspect-16-9 wp-has-aspect-ratio\"><div class=\"wp-block-embed__wrapper\">\n<iframe title=\"Pharmakogenetik Einf\u00fchrung\" width=\"800\" height=\"450\" src=\"https:\/\/www.youtube.com\/embed\/FEXF88x3xVM?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" referrerpolicy=\"strict-origin-when-cross-origin\" allowfullscreen><\/iframe>\n<\/div><\/figure>\n\n\n\n<p>Einer der Bl\u00f6cke, die wir k\u00fcrzlich zu unserer Plattform hinzugef\u00fcgt haben, ist der der <a href=\"https:\/\/adntro.com\/de\/dna-test-pharmakogenetik-bericht\/\" target=\"_blank\" rel=\"noreferrer noopener\"><span style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-light-green-cyan-color\">Pharmakogenetik<\/span><\/a>. Es ist die zust\u00e4ndige biologische Disziplin <strong>den Effekt genetischer Variabilit\u00e4t untersuchen<\/strong> einer Person in seiner <strong>Reaktion auf bestimmte Medikamente<\/strong>.<\/p>\n\n\n\n<div style=\"height:10px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\">Wir sind nicht alle gleich<\/h2>\n\n\n\n<p>Nicht alle von uns reagieren gleich auf Medikamente. Unsere Genetik kann bestimmen <strong>wie wirksam ist ein medikament<\/strong> in unserem K\u00f6rper oder wenn Ihr <strong>Nebenwirkungen<\/strong> sie k\u00f6nnen \u00e4lter sein. <\/p>\n\n\n\n<div style=\"height:10px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p>Medikamente sind heute eines der <strong><a href=\"https:\/\/adntro.com\/de\/blog\/pharmakogenetik\/diversity-genetics-clinical-essays\/\">Hauptursachen f\u00fcr Nebenwirkungen<\/a><\/strong>. Dies liegt daran, dass ein gewisser <strong>Homogenit\u00e4t bei Patienten<\/strong>, und daher werden die wirksamen und gut vertr\u00e4glichen Medikamente bei einigen auch bei anderen so sein.<\/p>\n\n\n\n<div style=\"height:10px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p>Aber nichts ist weiter von der Wahrheit entfernt, die Wahrheit ist, dass sie existieren <strong>Menschen, die ein Medikament schlechter vertragen<\/strong> oder was <strong>der Wirkungsgrad ist sehr gering<\/strong> in deinem K\u00f6rper. Das passiert, weil<strong> Wir sind keine homogene Gruppe<\/strong>, weisen wir eine gewisse genetische Variabilit\u00e4t auf, die sich darauf auswirkt, wie unser K\u00f6rper diese Medikamente verarbeitet.<\/p>\n\n\n\n<div style=\"height:10px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<figure class=\"wp-block-image size-full\"><img fetchpriority=\"high\" decoding=\"async\" width=\"960\" height=\"643\" src=\"http:\/\/adntro.com\/wp-content\/uploads\/2021\/08\/different-nationalities-5091375_960_720.jpg\" alt=\"genetische Variabilit\u00e4t\" class=\"wp-image-3434\" srcset=\"https:\/\/adntro.com\/wp-content\/uploads\/2021\/08\/different-nationalities-5091375_960_720.jpg 960w, https:\/\/adntro.com\/wp-content\/uploads\/2021\/08\/different-nationalities-5091375_960_720-300x201.jpg 300w, https:\/\/adntro.com\/wp-content\/uploads\/2021\/08\/different-nationalities-5091375_960_720-768x514.jpg 768w, https:\/\/adntro.com\/wp-content\/uploads\/2021\/08\/different-nationalities-5091375_960_720-18x12.jpg 18w\" sizes=\"(max-width: 960px) 100vw, 960px\" \/><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\">Genetik ist nicht die einzige im Spiel<\/h2>\n\n\n\n<p>Obwohl die Genetik eine grundlegende Rolle spielen wird, ist sie nicht der einzige Teilnehmer.<strong> Exogene Faktoren<\/strong> als die <strong>Di\u00e4t<\/strong> oder <strong>endogen<\/strong> als die <strong>Alter<\/strong> oder der <strong>Sex<\/strong> sie werden entscheidend sein, wenn es darum geht, ein bestimmtes Medikament mehr oder weniger gut vertragen oder wirksam zu machen.<\/p>\n\n\n\n<div style=\"height:10px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p>Was den genetischen Teil angeht, sind sie die <strong><a href=\"https:\/\/adntro.com\/de\/2020\/07\/24\/que-es-un-snp\/\">SNPs<\/a><\/strong> oder <strong>Polymorphismen<\/strong> f\u00fcr das Ergebnis verantwortlich sind. Dabei handelt es sich um Ver\u00e4nderungen an einer einzigen DNA-Base, die eine Genvariante schaffen, die bei der Verarbeitung eines Medikaments mehr oder weniger effektiv ist.<strong>.<\/strong><\/p>\n\n\n\n<div style=\"height:10px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<figure class=\"wp-block-image size-full\"><img decoding=\"async\" width=\"1024\" height=\"326\" src=\"http:\/\/adntro.com\/wp-content\/uploads\/2021\/08\/Captura-de-pantalla-2020-07-24-a-las-11.34.09-1024x326-1.png\" alt=\"SNPs\" class=\"wp-image-3433\" srcset=\"https:\/\/adntro.com\/wp-content\/uploads\/2021\/08\/Captura-de-pantalla-2020-07-24-a-las-11.34.09-1024x326-1.png 1024w, https:\/\/adntro.com\/wp-content\/uploads\/2021\/08\/Captura-de-pantalla-2020-07-24-a-las-11.34.09-1024x326-1-300x96.png 300w, https:\/\/adntro.com\/wp-content\/uploads\/2021\/08\/Captura-de-pantalla-2020-07-24-a-las-11.34.09-1024x326-1-768x245.png 768w, https:\/\/adntro.com\/wp-content\/uploads\/2021\/08\/Captura-de-pantalla-2020-07-24-a-las-11.34.09-1024x326-1-18x6.png 18w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\">Arzneimitteltoleranz<\/h2>\n\n\n\n<div style=\"height:10px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p>Wenn es darum geht <strong>Toleranz<\/strong> gegen\u00fcber einem bestimmten Medikament ist normalerweise <strong><a href=\"https:\/\/es.wikipedia.org\/wiki\/Enzima\" target=\"_blank\" aria-label=\"undefiniert (\u00f6ffnet sich in einem neuen Tab)\" rel=\"noreferrer noopener\"><span class=\"has-inline-color has-light-green-cyan-color\">Enzyme<\/span><\/a><\/strong> verantwortlich f\u00fcr <strong><a aria-label=\"undefiniert (\u00f6ffnet sich in einem neuen Tab)\" href=\"https:\/\/es.wikipedia.org\/wiki\/Metabolismo\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"has-inline-color has-light-green-cyan-color\">verstoffwechseln<\/span><\/a><\/strong> und vermeide so <strong>Toxizit\u00e4t<\/strong>. Wenn Ihre Genvariante f\u00fcr dieses Enzym a <strong>geringe Effizienz des Wirkstoffstoffwechsels<\/strong>, dies f\u00fchrt zu a <strong>erh\u00f6hte Toxizit\u00e4t<\/strong>. Daher wird das Wirkstoffmolek\u00fcl nicht schnell aus dem K\u00f6rper ausgeschieden, und diese Toxizit\u00e4t kann zu <strong>Nebenwirkungen<\/strong> wie Durchfall, Erbrechen, Blutungen usw.<\/p>\n\n\n\n<div style=\"height:10px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<figure class=\"wp-block-image size-full\"><img decoding=\"async\" width=\"880\" height=\"372\" src=\"http:\/\/adntro.com\/wp-content\/uploads\/2021\/08\/stomach-health-diet-dessert-eating-belly-sugar-sweets-overeater-overeating.jpg\" alt=\"Drogenvertr\u00e4glichkeit\" class=\"wp-image-3432\" srcset=\"https:\/\/adntro.com\/wp-content\/uploads\/2021\/08\/stomach-health-diet-dessert-eating-belly-sugar-sweets-overeater-overeating.jpg 880w, https:\/\/adntro.com\/wp-content\/uploads\/2021\/08\/stomach-health-diet-dessert-eating-belly-sugar-sweets-overeater-overeating-300x127.jpg 300w, https:\/\/adntro.com\/wp-content\/uploads\/2021\/08\/stomach-health-diet-dessert-eating-belly-sugar-sweets-overeater-overeating-768x325.jpg 768w, https:\/\/adntro.com\/wp-content\/uploads\/2021\/08\/stomach-health-diet-dessert-eating-belly-sugar-sweets-overeater-overeating-18x8.jpg 18w\" sizes=\"(max-width: 880px) 100vw, 880px\" \/><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\">Arzneimittelwirksamkeit<\/h2>\n\n\n\n<div style=\"height:10px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p>Stattdessen, wenn es darum geht <strong>Wirksamkeit<\/strong> eines Medikaments sind dies Genvarianten, die die <strong>Wirkstoffmolek\u00fcl-Targets<\/strong>. Wenn die Genvariante ein &quot;geeigneteres Ziel&quot; erzeugt, hat das Medikament eine gr\u00f6\u00dfere Wirkung auf Ihren K\u00f6rper und daher <strong>Sie ben\u00f6tigen weniger Dosen<\/strong> um den gleichen Effekt zu erzielen. Im Gegenteil, wenn Ihr &quot;Ziel nicht so geeignet ist&quot; <strong>du wirst mehr brauchen<\/strong> des Medikaments, um die gleiche Wirkung zu erzielen, ja, Sie sollten Ihre Toleranz kennen, da Sie bei einer hohen Dosis toxische Wirkungen haben k\u00f6nnen.<\/p>\n\n\n\n<div style=\"height:10px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"960\" height=\"640\" src=\"http:\/\/adntro.com\/wp-content\/uploads\/2021\/08\/disease-4392152_960_720.jpg\" alt=\"Wirksamkeit von Arzneimitteln\" class=\"wp-image-3431\" srcset=\"https:\/\/adntro.com\/wp-content\/uploads\/2021\/08\/disease-4392152_960_720.jpg 960w, https:\/\/adntro.com\/wp-content\/uploads\/2021\/08\/disease-4392152_960_720-300x200.jpg 300w, https:\/\/adntro.com\/wp-content\/uploads\/2021\/08\/disease-4392152_960_720-768x512.jpg 768w, https:\/\/adntro.com\/wp-content\/uploads\/2021\/08\/disease-4392152_960_720-18x12.jpg 18w\" sizes=\"(max-width: 960px) 100vw, 960px\" \/><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\">Fragen Sie immer Ihren Arzt<\/h2>\n\n\n\n<div style=\"height:10px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p>Bei allem, was wir gesehen haben, werden Sie erkannt haben, dass es wichtig ist, unsere Vertr\u00e4glichkeit \/ Wirksamkeit gegen\u00fcber Medikamenten zu kennen, aber <strong>Sie sollten die Dosis niemals basierend auf diesen Ergebnissen variieren<\/strong>. Auch wenn Sie die <a href=\"https:\/\/adntro.com\/de\/\">DNA-Tests<\/a> mit ADNTRO, immer <strong>Sie sollten Ihren Arzt konsultieren<\/strong> und \u00fcbermitteln Sie ihm Ihre pharmakogenetischen Ergebnisse, damit er derjenige ist, der bestimmt, wie Sie Ihre Medikamente einnehmen sollen.<\/p>","protected":false},"excerpt":{"rendered":"<p>Einer der Bausteine, die wir k\u00fcrzlich zu unserer Plattform hinzugef\u00fcgt haben, ist der der Pharmakogenetik. Es ist die biologische Disziplin, die daf\u00fcr verantwortlich ist, die Auswirkungen der genetischen Variabilit\u00e4t eines Individuums in seiner Reaktion auf bestimmte Medikamente zu untersuchen. Wir sind nicht alle gleich Wir reagieren nicht alle gleich auf Medikamente. Unsere Genetik kann bestimmen, [\u2026]<\/p>","protected":false},"author":8,"featured_media":3434,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[36],"tags":[15,37,18,38],"class_list":["post-1041","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-farmacogenetica-farmacogenomica","tag-adn","tag-farmacogenetica","tag-genetica","tag-medicacion"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v22.0 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Farmacogen\u00e9tica: Conoce c\u00f3mo te afectan los medicamentos<\/title>\n<meta name=\"description\" content=\"La farmacogen\u00e9tica, encargada de estudiar el efecto de la variabilidad gen\u00e9tica de un individuo en su respuesta a determinados medicamentos.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" 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